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What are talismans in Path of Exile 2?

Talismans are two-handed melee weapons that need Strength and Intelligence and are used for shapeshifting: wielding one in your active weapon set turns you into its form, such as a bear, werewolf or wyvern, and gives that form's basic attack.

Unique talismans

Amor Mandragora, Spiteful Floret, Hysseg's Claw, The Flesh Poppet, Surge of the Tide and Fury of the King are the unique talismans we stock. Some grant extra skills, such as Molten Crash from Fury of the King.

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POE 2 Talismans Questions, Answered

What does a talisman do?

It shapeshifts you into its form and gives that form's attack.

Are talismans one-handed?

No, they are two-handed.