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What are the keys and organs for?
They open the Pandemonium Event, the Uber Tristram fight. In Hell, the Key of Terror drops from the Countess, the Key of Hate from the Summoner and the Key of Destruction from Nihlathak.
From keys to the Hellfire Torch
One key of each kind in the Horadric Cube, in Harrogath on Hell, opens a portal to Lilith, Uber Duriel or Uber Izual. Between them they drop Diablo's Horn, Baal's Eye and Mephisto's Brain. Those three organs together open Uber Tristram, who drops the Hellfire Torch.
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D2R Keys & Organs Questions, Answered
How many keys do I need for Uber Tristram?
Three of each key opens all three portals, which gives you the three organs.
What drops the Hellfire Torch?
Uber Tristram, the end of the Pandemonium Event.
What is an Organ Set?
Diablo's Horn, Baal's Eye and Mephisto's Brain together: everything needed to open Uber Tristram.
